If you're driving from California's Central Valley or the Bay Area to Reno for Worldcon and haven't been up that way lately, be warned that there is ongoing significant construction work on I-80. In particular, between Emigrant Gap and Cisco Grove westbound eastbound traffic is limited to one narrow lane and is subject to significant delays. Also, the Donner Summit rest areas are closed, so plan your rest stops accordingly.
Be patient and give yourself extra time to get over the hill to Reno.
Update, 2200: Corrected direction. It's traffic from Sacramento and the Bay Area toward Reno that is affected.